FAQ

Improvements in wound healing were shown in multiple studies:

• Decrease in diabetic foot ulcer size of 55% (median) within 2 weeks [source 1].
• Wound closure in 60% of chronic wounds, after an average treatment period of 7 weeks [source 2].
• Wound closure in 47% of hard-to-heal and mostly (severely) infected wounds; all wounds showed substantial reduction in wound size (average 90%) [source 3].
• Wound closure and wound size reduction in venous leg ulcers [source 4, a randomized controlled trial].

PLASOMA has also been shown to reduce the number of bacteria (Staphylococcus aureus, in wounds [source 1]; Pseudomonas aeruginosa, on intact skin [source 5]).

Lastly, there are indications that PLASOMA stimulates the microcirculation [source 5 and unpublished data].

Some cases have been detailed in case study reports

The frequency and the number of treatments depends on, among others, the type of chronic wound and the size. Typically, the treatment will be done 1 to 2 times per week for several weeks. PLASOMA cold plasma treatment itself is only 2 minutes.

PLASOMA is CE-certified and available for the market. For product information or to request a product demonstration please contact our sales department via info@plasmacure.nl

PLASOMA cold plasma application is available at multiple wound care centres in the Netherlands and other countries. Send an e-mail to info@plasmacure.nl to receive more information. For other actual information please subscribe to our newsletter.

Plasma is ionized gas, the the so-called 4^th stage of matter (1. solid, 2. liquid, 3. gas, 4. plasma). A plasma is created by adding energy to a gas. Plasma is a mix of electrons and ions, reactive species, UV radiation, visible light, electromagnetic fields and heat. Plasma exists in nature, for example the sun, which is so hot that it consists of a hot plasma. With an artificially produced plasma it is possible to keep the temperature low, not much higher than body temperature. We call this a cold plasma, which can be applied in or on the human body.

Cold plasma kills bacteria, even antibiotic resistant ones, and it inactivates bacteria in biofilm. Additionally, it can improve local blood supply (microcirculation) and stimulate cells to grow (cell proliferation) and move (cell migration).

Read more on this topic in the whitepaper ‘Stimulation of wound healing using cold plasma’. 

All types of chronic wounds can be treated with cold plasma. For example: diabetic foot wounds, venous leg wounds, bedsores, hard-to-heal burn wounds and infected postoperative wounds.

Various studies are in progress regarding cold plasma as a treatment for cancer. Cold plasma is also used in dentistry for disinfection and in dermatology.

Cold plasma treatment is safe. Side effects are mild, local, transient and well tolerated. This has been demonstrated through clinical studies with PLASOMA as well as with other cold plasma devices.
Literature on other cold plasma devices

Sources for PLASOMA:

• Cold plasma treatment is safe for diabetic foot ulcers and decreases Staphylococcus aureus bacterial load – Journal of Wound Care, Vol. 32, No.4 (2023)
• Antibacterial and safety tests of a flexible cold atmospheric plasma device for the stimulation of wound healing – Appl Microbiol Biotechnol 105, 2057-2070 (2021)

Worldwide chronic wounds affect 140 million people. In the Netherlands the number of people suffering from chronic wounds is 500.000.

Chronic wounds have a high impact on quality of life and on survival rate. For example, the 5-year survival rate in diabetic foot ulcers is even lower compared to prostate cancer and breast cancer. Also chronic wounds result in amputations in 15% of the diabetic foot ulcers and 5% of the venous leg ulcers.

On average, non-healing wound costs €13.500 per year.